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Channer, B*, Matt, SM*, Nickoloff-Bybel, EA, Agarwal, Y, Pappa, V, Wickman J, and Gaskill, P.J. Dopamine, Immunity and Disease. Pharmacological Reviews. January 2023 doi: 10.1124/pharmrev.122.000618

Gaskill, P.J. and Khoshbouei, H. Dopamine and norepinephrine are embracing their immune side and so should we. Current Opinion in Neurobiology. September 2022 doi; 10.1016/j.conb.2022.102626

Emmanuel, K, Runner, K, Johnson, HS, Brodnik, Z, Lamberty, B, Morrissey, B, Acharya, A, Byareddy, S, Espana, R, Fox, HS and Gaskill, PJ. Deprenyl reduces inflammation during acute SIV infection. iScience, April 2022 doi: 10.1016/j.isci.2022.104207

Mackie, PM, Gopinath, A, Montas, D, Nielsen, A, Nolan, RA, Runner, K, Matt, SM, McNamee, J, Riklan, J, Adachi, K, Doty, A, Ramirez-Zamora, A, Yan, L, Gaskill, PJ, Streit, WJ, Okun, MS, Khoshbouei, H. Functional characterization of the biogenic amine transporters on human macrophages. JCI Insight, January 2022. doi: 10.1172/jci.insight.151892.

Gaskill, Peter J., Fields, Jerel Adam, Langford, Dianne T., Stauch, Kelly and Williams, Dionna W. Editorial: Advances in Understanding NeuroHIV Associated Changes in Neuroimmune Communication in the Combined Anti-retroviral Therapy (cART) Era. Frontiers in Neurology, August 2021. doi:10.3389/fneur.2021.763448

Nickoloff-Bybel, EA, Festa, LK, Meucci, O and Gaskill, PJ. Co-receptor signaling in the pathogenesis of neuroHIV. Retrovirology 18, 24 (2021). doi: 10.1186/s12977-021-00569-x

Matt, SM, Nickoloff-Babel, EA, Rong, Y, Runner, K, Johnson, H, O'Connor, MH, Haddad, EK, and Gaskill, PJ. Dopamine Levels Induced by Substance Abuse Alter Efficacy of Maraviroc and Expression of CCR5 Conformations on Myeloid Cells: Implications for NeuroHIV. Frontiers in Immunology. April 2021.  10.3389/fimmu.2021.663061

Nickoloff-Bybel, EA, Calderon, TA, Gaskill, PJ and Berman JW. HIV Neuropathogenesis in the Presence of a Disrupted Dopamine System. J Neuroimmune Pharmacol. June 2020.doi: 10.1007/s11481-020-09927-6

Nolan, R.A. , Reeb, K.L, Rong, Y., Matt, S. M., Johnson, H. S., Runner, K., and Gaskill, P.J. (2019). Dopamine activates NF-κB and primes the NLRP3 inflammasome in primary human macrophages. Brain Behav Immun – Health. 2(100030), 1-17. 2020 Feb. doi: 10.1016/j.bbih.2019.100030

Nickoloff, E.A., Mackie, P., Runner, K., Matt, S.M., Khoshbouei, H. and Gaskill P.J., (2019) Dopamine Increases HIV Entry into Macrophages by increasing Calcium release via an alternative signaling pathway. Brain Behav Immun, 82, 239-252. 2019 Nov. PMCID: PMC6941734 doi: 10.1016/j.bbi.2019.08.191

Matt, SM and Gaskill, Peter J. (2019). Where dopamine and immune cells interact: Implications for health and disease. J Neuroimmune Pharmacol. 2019 May 11. doi:10.1007/s11481-019-09851-4​

Nolan RAMuir RRunner KHaddad EKGaskill PJ. Role of Macrophage Dopamine Receptors in Mediating Cytokine Production: Implications for Neuroinflammation in the Context of HIV-Associated Neurocognitive Disorders. J Neuroimmune Pharmacol. 2019 Mar;14(1):134-156. doi: 10.1007/s11481-018-9825-2. Epub 2018 Dec 5.

 

Gaskill PJ, Miller DR, Gamble-George J, Yano H, Khoshbouei H. HIV, Tat and  dopamine transmission. 

Neurobiol Dis. 2017 Sep;105:51-73. doi: 10.1016/j.nbd.2017.04.015. Epub 2017 Apr 27. Review. PMID: 28457951

Gaskill PJ, Yano HH, Kalpana GV, Javitch JA, Berman JW. Dopamine receptor activation increases HIV entry into primary human macrophages. PLoS One. 2014 Sep 30;9(9):e108232. doi: 10.1371/journal.pone.0108232. eCollection 2014. PMID: 25268786

Gaskill PJ, Carvallo L, Eugenin EA, Berman JW.  Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse. J Neuroinflammation. 2012 Aug 18;9:203. doi: 10.1186/1742-2094-9-203. PMID: 22901451

Gaskill PJ, Calderon TM, Luers AJ, Eugenin EA, Javitch JA, Berman JW. Human immunodeficiency virus (HIV) infection of human macrophages is increased by dopamine: a bridge between HIV-associated neurologic disorders and drug abuse. Am J Pathol. 2009 Sep;175(3):1148-59. doi:10.2353/ajpath.2009.081067. Epub 2009 Aug 6. PMID: 19661443

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Selected Publications

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