Gaskill Lab News Archives
June 2023
The Gaskill lab received a new R61/R33 award from NIDA to study the impact of stimulant evoked dopamine release on the development of neuroHIV!!!
Dr. Stephanie Matt, Breana Channer and Alexis Brantly presented posters at the annual PNIRS meeting in Boulder, Colorado.
May 2023
Breana Channer, Dayna Robinson and Dr. Stephanie Matt presented their posters at the 2023 ASPET meeting.
Dr. Stephanie Matt received a K01 from the NIMH to study the impact of anti-depressants on inflammation and HIV infection in macrophages!!!!!
April 2023
Dr. Gaskill speaking on keynote panel at the Drexel Emerging Graduate Scholars Conference (DEGS) on April 20th. You can watch the panel here.
March 2023
Congratulations to Dr. Stephanie Matt for receiving a catecholamine society fellowship and being selected for an oral presentation at the annual ASPET meeting!!!
February 2023
Congratulations to Tofunmi Oteju for passing her preliminary exam!!!
January 2023
Congratulations to Dayna Robinson for receiving an ASPET travel award to attend the 2023 ASPET meeting in St. Louis!!!
Our newest review "Dopamine, Immunity and Disease" is published in pharmacological reviews .. this review is a beast and was 2 years in the making!!!! Congratulations to all authors, particularly Breana Channer and Dr. Stephanie Matt, who led the effort.
Dr. Stephanie Matt receives a pilot award from the Temple / Drexel Comprehensive NeuroAIDs Center!!
Congratulations to Alexis Brantly, Breana Channer, and Stephanie Matt on their successful submission of F and K fellowships!!
November 2022
Congratulations to Breana Channer for receiving the Drexel Alumni Association Travel Award!!!
October 2022
Breana Channer wins 3rd place for her poster presentation at Discovery Day!!! Congratulations Breana!!!
Alexis Brantly, Breana Channer, Teresa Lupone, Dayna Robinson and Tofunmi Oteju present posters from the Gaskill Lab at Discovery day 2022.
Breana Channer, Alexis Brantly, Tofunmi Oteju attend HCS101 in Pittsburgh to further develop the Gaskill Lab capacity for high content imaging and analysis.
High content imaging work from the Gaskill Lab published in paper accepted to Mucosal Immunology on "Severity of neonatal influenza infection is driven by type I interferon and oxidative stress" from the Carey Lab.
September 2022
Dr. Gaskill gives a seminar entitled "Myeloid Dopamine Receptors Drive Inflammation through non-cannonical signaling pathways" at Europhysiology2022 in Copenhagen.
Drs. Gaskill and Klase receive a five-year NIH R01 from the National Institutes of Drug Abuse entitled "Benzodiazepine mediated mechanisms of transcriptional semi-quiescence in discrete myeloid populations." This research will focus on the HIV replication dynamics in primary macrophages and syngeneic, iPSC-derived macrophages and microglia, evaluating these processes and how they are affected by benzodiazepines.
Dr. Gaskill publishes an opinion paper in Current Opinion in Neurobiology with Dr. Khoshbouei. This paper, entitled "Dopamine and norepinephrine are embracing their immune side and so should we" focuses on the growing understanding of the immunologic role of catecholamines.
August 2022
Congratulations to Breana Channer for her appointment as a National Research Service Award (NRSA) pre-doctoral fellow on Drexel University’s Interdisciplinary and Translational Research Training Grant in NeuroAIDS, funded by the National Institutes of Health (National Institute of Mental Health grant T32-MH079785).
October 2021
Breana Channer receives 3rd place for her poster presentation on "Optimizing culture conditions for measurement of human monocyte derived macrophage inflammatory activity" at Discovery Day 2021!!
Dr. Emily Nickoloff-Bybel finished her last day in the Gaskill Lab and is moving on to the University of Pennsylvania to do her post-doctoral training with Dr. Kelly Jordan-Sciutto. Congratulations Dr. Nickoloff-Bybel!!
Dr. Stephanie Matt published her review about "Targeting neurotransmitter-mediated inflammatory mechanisms of psychiatric drugs to mitigate the double burden of multimorbidity and polypharmacy" in Brain, Behavior and Immunity - Health.
September 2021
Congratulations to Dr. Emily Nickoloff-Bybel, who defended a fantastic thesis entitled "The Impact of Dopamine Receptor Signaling on Myeloid Cell Function: Implications for the Pathogenesis of NeuroHIV." Fantastic job Emily!!!!
The Gaskill Lab is looking to hire a new lab technician to work with both the Gaskill and Klase labs on projects involving the isolation, infection and analysis of immune cells from human blood. Please reach out to us if you are interested.
Dr. Stephanie Matt published an excellent review in Brain, Behavior and Immunity - Health on "Targeting neurotransmitter-mediated inflammatory mechanisms of psychiatric drugs to mitigate the double burden of multimorbidity and polypharmacy". Well-done Stephanie!!!
COVID News Blackout
December 2020
Hannah Johnson receives Winter Term Mini-grant from Drexel to continue her senior thesis research doing high-content analysis of dopamine mediated changes in NF-kB activity in macrophages
November 2020
Dr. Gaskill is receives the New Investigator of the Year award from Drexel University College of Medicine.
Drs. Gaskill and Matt receive a grant from the W.W. Smith Charitable Trust Foundation for which Dr. Matt will lead a project examining "Dopamine induced by substance abuse exacerbates HIV-associated neuroinflammation through epigenetic regulation"
September 2020
An R01 collaboration on the impact of cannabidiol on HIV-associated inflammation with Dr. Dionna Williams at Johns Hopkins is funded. Dr. Gaskill is a co-I and will be investigating changes in the function of tissue specific macrophages in response to SIV, ART and cannabidiol.
June 2020
Lab resumes operation at 33% capacity on June 15th
May 2020
Emily Nickoloff-Bybel and Dr. Stephanie Matt present posters at the Virtual Dopamine meeting (ViDA) on May 19th
March 2020
Lab pauses operation for COVID-19 on March 18th
Received Notice of Award for NIDA R21 examining the impact of dopamine on IL-1beta production mediated by NF-kB and the NLRP3 inflammasome
Emily Nickoloff-Bybel gives a fantastic works-in-progress on her studies examining the molecular mechanisms underlying the dopamine mediated increase in HIV entry
February 2020
Samy Manikanda is awared the Medical Student Summer Research Fellowship (MSSRF).
Kimberley Bonar will return to the Gaskill Lab this summer as a part of Drexel's Summer Undergraduate Research Fellowship (SURF) program.
December 2019
Emily Nickoloff-Bybel is awarded the Mary Shaw travel award.
Rotation Student Katelyn Reeb successfully gave her rotation talk on the NLRP3 Inflammasome.
Dr. Peter Gaskill gave a talk about the role of dopamine in NeuroHIV at the Puerto Rico Neuroscience Conference on December 7th, 2019.
November 2019
Hannah Johnson is awarded First Place in the Undergraduate Poster presentation at Discovery Day 2019
Dr. Stephanie Matt, Emily Nickoloff-Bybel, Hannah Johnson and Katie Reeb present posters at Discovery Day.
Yi Rong successfully defends his master's thesis entitled "High-Content Screening Analysis of Dopamine-Mediated Changes in Human Macrophages in the context of HIV infection."
October 2019
Peter Gaskill, Emily Nickoloff-Bybel, Stephanie Matt and Hannah Johnson will present posters at the annual Society for Neuroscience in Chicago on Wednesday afternoon, October 23.
Gaskill Lab attends the annual CX7 users conference at the Forrestal convention center in Princeton, NJ.
Emily Nickoloff-Bybel presents "Dopamine increases HIV entry into macrophages via an alternative, calcium dependent pathway" at the annual Institute for Molecular Medicine and Infectious Disease HIV symposium
Emily Nickoloff-Bybel wins 2nd place for her poster presentation on the role of calcium signaling in the dopamine mediated increase in HIV infection at the Mid-Atlantic Pharmacology Society (MAPS-ASPET) at Temple University
September 2019
Dr. Peter Gaskill presents "The role of dopamine in modulating the NF-kB and inflammasome pathways in macrophages" at the Drexel Immunomodulation seminar series
August 2019
Emily Nickoloff-Bybel's study "Dopamine increases HIV entry into macrophages by increasing calcium release via an alternative signaling pathway" is accepted to Brain, Behavior and Immunity.
Dr. Stephanie Matt's newest paper entitled "Dopaminergic impact of cART and anti-depressants on HIV Neuropathogenesis in older adults" is published in Brain Research.
Emily Nickoloff-Bybel is chosen as a National Research Service Award (NRSA) pre-doctoral fellow on Drexel University’s Interdisciplinary and Translational Research Training Grant in NeuroAIDS.
June 2019
Dr. Stephanie Matt receives the 2019 Brody Family Medical Trust Fellowship
May 2019
Dr. Peter J. Gaskill is featured in "The Drive To Know" in this months Drexel University College of Medicine Alumni Magazine.
Our latest article, "Where is Dopamine and how do Immune cells See it?: Dopamine-Mediated Immune cell functions in health and disease." was published in the Journal of Neuroimmune Pharmacology.
April 2019
Rachel Nolan successfully defends her thesis entitled "Role of Dopamine in the Modulation of Macrophage-Mediated Inflammation: Implications for the Neuropathogenesis of NeuroHIV and Drug Abuse."